Exploring the New Frontier of PD-1 Dimerization in T Cell Regulation: New Hope for Cancer Immunotherapy and autoimmune diseases
Programmed cell death protein 1 (PD-1), expressed on T cells, is a critical immune checkpoint molecule that plays a vital role in maintaining immune homeostasis by preventing overactivation of T cells. PD-1 achieves this by binding to its ligands, PD-L1 and PD-L2, leading to the inhibition of T cell activity. This mechanism is crucial for …